Multiple pathways exist that make allergy inflammation worse. These are 3 to look out for:
Biochemical Pathways of Inflammation (3 key pathways to watch out for):
Histamine Pathway
a. Histamine is primarily produced in the gut, often by ‘bad’ microbes.
b. HistaDINE is the precursor molecule for histamine production.
c. Dietary sugar stimulates ‘bad’ microbes like Yeast, Candida, and harmful bacteria.
Arachidonic Acid Pathway
a. This pathway is related to inflammation caused by animal-derived cholesterol.
TNF-a, IL-6 (Tumor Necrosis Factor Alpha and Interleukin-6)
a. These cytokines cause a dysfunctional immune response.
b. Vitamin D deficiency is known to cause elevations in TNF-a and IL-6.
c. Phytonutrients can help block TNF-a and IL-6, reducing inflammation.
References:
https://pubmed.ncbi.nlm.nih.gov/9305226/
https://pubmed.ncbi.nlm.nih.gov/3083171/
https://pubmed.ncbi.nlm.nih.gov/1401652/
Dysfunctional immune inflammation is associated with a range of conditions, including: Eczema, Allergies, UTIs, Irritable Bowel (IBS), IBD, Crohn’s/Colitis, SIBO, Candida, GERD, Viral illnesses, Autism, Multiple Sclerosis, Lupus, Rheumatoid Arthritis, Mixed Connective Tissue Disorder, Sjögren’s, Autoimmune Thyroiditis, Migraine Headaches, Neuropathy, and Fibromyalgia.